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Topoisomerase expression in oral squamous cell carcinoma: relationship with cancer stem cells profiles and lymph node metastasis
(WILEY-BLACKWELLHOBOKEN, 2013-08-02)
BACKGROUND: The relationship between predictive proteins and tumors presenting cancer stem cells (CSCs) profiles in oral tumors is still poorly understood. This study aims to identify the relationship between topoisomerases ...
Peptides from yacg protein as inhibitors of DNA gyrase and human topoisomerase II alpha
(Wiley-Blackwell, 2014-09-01)
Expressão de topoisomerase II alfa e de caspase-3 ativada em lesão intra-epitelial cervical escamosa de baixo grau
(Universidade Federal de São Paulo (UNIFESP), 2008-03-26)
Purpose: To evaluate the correlation between the expression of topoisomerase II alpha, active caspase-3 and infection with human papillomavirus in low-grade cervical intraepithelial lesion and in the normal cervix, and ...
Topoisomerase II alpha Status in Renal Medullary Carcinoma: Immuno-Expression and Gene Copy Alterations of a Potential Target of Therapy
(Elsevier Science IncNew YorkEUA, 2009)
Design and synthesis of peptides from bacterial ParE toxin as inhibitors of topoisomerases
(Elsevier France-editions Scientifiques Medicales Elsevier, 2012-08-01)
Toxin-antitoxin (TA) proteic systems encode a toxin and an antitoxin that regulate the growth and death of bacterial cells under various stress conditions. The ParE protein is a toxin that inhibits DNA gyrase activity and ...
Design and synthesis of peptides from bacterial ParE toxin as inhibitors of topoisomerases
(Elsevier France-editions Scientifiques Medicales Elsevier, 2012-08-01)
Toxin-antitoxin (TA) proteic systems encode a toxin and an antitoxin that regulate the growth and death of bacterial cells under various stress conditions. The ParE protein is a toxin that inhibits DNA gyrase activity and ...
Measurement of drug-stabilized Topoisomerase II cleavage complexes by Flow Cytometry
(Wiley, 2017-07)
The poisoning of Topoisomerase II (Top2) has been found to be useful as a therapeutic strategy for the treatment of several tumors. The mechanisms of these agents involves a drug-mediated stabilization of a Top2-DNA complex, ...
Peptides from yacg protein as inhibitors of DNA gyrase and human topoisomerase II alpha
(Wiley-Blackwell, 2015)